赵洪源，工学博士，讲师。2023年06月毕业于南京农业大学食品科技学院酶工程实验室。参与国家自然科学基金面上项目1项，国家自然科学基金地区科学基金项目1项，以参与人身份获河南省科学技术进步二等奖。以第一作者在Pharmacological research, Food & function, Food Science and Human Wellness等期刊发表文章6篇，其中2023年ESI高被引文章1篇，另参与发表论文20余篇。主要研究方向是功能性食品，开展优质益生菌的筛选和功能成分的分离纯化，并探究益生菌和功能性成分对代谢型疾病的调节机制。
一、 主持或参与的科研项目
1． 永利集团红柳优秀青年人才支持计划（第五批），在研，主持；
2． 永利集团博士科研启动基金，2023年12月立项，在研，主持；
3． 甘肃省2023年知识产权运用项目，2023年12月立项，在研，主持。
二、 代表性成果
1． Zhao Hongyua, Lu Zhaoxin, Lu Yingjian. The potential of probiotics in the amelioration of hyperuricemia[J]. Food & function, 2022, 13(5): 2394-2414. （高被引文章）（中科院一区）
2． Zhao Hongyuan, Chen Xiaoyu, Meng Fanqiang, Zhou Libang, Pang Xinyi, Lu Zhaoxin, Lu Yingjian. Ameliorative effect of Lacticaseibacillus rhamnosus Fmb14 from Chinese yogurt on hyperuricemia[J]. Food Science and Human Wellness, 2023, 12(4): 1379-1390. （中科院一区）
3． Zhao Hongyuan, Chen Xiaoyu, Zhang Li, Tang Chao, Meng Fanqiang, Zhou Libang, Zhu Ping, Lu Zhaoxin, Lu Yingjian. Ingestion of Lacticaseibacillus rhamnosus Fmb14 prevents depression-like behavior and brain neural activity via the microbiota-gut-brain axis in colitis mice[J]. Food & function, 2023, 14(4): 1909-1928. （中科院一区）
4． Zhao Hongyuan, Chen Xiaoyu, Zhang Li, Meng Fanqiang, Zhou Libang, Pang Xinyi, Lu Zhaoxin, Lu Yingjian. Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis[J]. Pharmacological research, 2022: 106350. （中科院一区）
5． Zhao Hongyuan, Chen Xiaoyu, Zhang Li, Meng Fanqiang, Zhou Libang, Zhu Ping, Lu Zhaoxin, Lu Yingjian. Lacticaseibacillus rhamnosus Fmb14 ameliorates hyperuricemia-induced hepatocyte pyroptosis via NLRP3 inflammasome cascade Inhibition[J]．Food Science and Human Wellness (Accepted). （中科院一区）
6． Zhao Hongyuan and Yun Jianmin, Isolation, identification and fermentation conditions of highly acetoin-producing acetic acid bacterium from Liangzhou fumigated vinegar in China[J] . Annals of Microbiology, 2016, 66(1):279-288.( 中科院四区，)
7． Tang Chao, Zhao Hongyuan, Kong Liangyu, Meng Fanqiang, Zhou Libang, Lu Zhaoxin, Lu Yingjian. Probiotic Yogurt Alleviates High-Fat Diet-Induced Lipid Accumulation and Insulin Resistance in Mice via the Adiponectin Pathway[J]. Journal of Agricultural and Food Chemistry, 2023, 71(3): 1464-1476. （共同一作）（中科院一区）
8． Chen Xiaoyu, Zhao Hongyuan, Lu Yajun, Liu Huawei, Meng Fanqiang, Lu Zhaoxin, Lu Yingjian. Surfactin Mitigates a High-Fat Diet and Streptozotocin-Induced Type 2 Diabetes through Improving Pancreatic Dysfunction and Inhibiting Inflammatory Response[J]. International Journal of Molecular Sciences, 2022, 23(19). （中科院二区）
9． Chen Xiaoyu, Zhao Hongyuan, Lu Yajun, Meng Fanqiang, Lu Zhaoxin, Lu Yingjian. Surfactin Mitigates Dextran Sodium Sulfate-Induced Colitis and Behavioral Disorders in Mice by Mediating Gut-Brain-Axis Balance[J]. Journal of Agricultural and Food Chemistry, 2023. （中科院一区）
10． Chen X, Zhao H, Meng F, et al. Ameliorated effects of a lipopeptide surfactin on insulin resistance in vitro and in vivo[J]. Food Science & Nutrition, 2022, 10(7): 2455-2469. （中科院三区）
11． Chen Xiaoyu, Lu Yajun, Shan Mengyuan, Zhao Hongyuan, Lu Zhaoxin, Lu Yingjian. A mini-review: mechanism of antimicrobial action and application of surfactin[J]. World Journal of Microbiology & Biotechnology, 2022, 38(8). （中科院三区）
12． Meng Fanqiang, Lyu Yunbin, Zhao Hongyuan, Lyu Fengxia, Bie Xiaomei, Lu Yingjian, Chen Yihua, Lu Zhaoxin. LsrR-like protein responds to stress tolerance by regulating polysaccharide biosynthesis in Lactiplantibacillus plantarum[J]. International Journal of Biological Macromolecules, 2023, 225: 1193-1203. （中科院一区）
13． Chen Xiaoyu, Zhao Hongyuan, Meng Fanqiang, Zhou Libang, Lu Zhaoxin, Lu Yingjian. Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin. Food Science and Human Wellness. 2023（Accepted）（中科院一区）
14． 赵洪源,贠建民,邵晓庆,丹.凉州熏醋酿造中高产乙偶姻醋酸菌菌株筛选及其发酵条件优化[J].食品科学,2015,36(15):98-104.
15． 陆兆新,赵洪源,吕凤霞,别小妹,赵海珍. 具有预防或缓解高尿酸血症的鼠李糖乳杆菌fmb14及应用[P]. 江苏省：CN114574382A,2022-06-03. (第二发明人，导师第一)
三、 联系方式
通讯地址：兰州理工老员工命科学与工程学院（兰州市七里河区彭家坪路36号）
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